Statistical genetics Term Paper Example | Topics and Well Written Essays - 1250 words

Statistical genetics - Term Paper Example Genetic association assists in finding out if a trait associates with a genetic variation. Statistical exploration of the responsible factors helps to accomplish the objectives. Ideally, genetic linkage is a characteristic of proximal location of genes on a chromosome to cause group inheritance. There is a less likelihood of separation of genes located together. Scientists use linkage maps to determine the position of genetic markers or genes relative to one another. Newton Morton developed a statistical test, LOD score useful in linkage analysis. LOD scores relate the likelihood of finding test data in case there is a linkage in the loci (Posthuma 175). Linkage analysis falls into two groups namely parametric and non-parametric. Parametric analysis adopts that models unfolding the maker and trait loci are well known without any error while the nonparametric analysis makes diminutive axioms regarding the trait model or simply put, it ponders all pedigree information. Linkage disequilibrium is used to describe DNA recombination. Generally, linkage concerns the physical segments of the genome that gives characteristics to a given trait. Various statistical methodologies have been useful in detecting genetic variation and analyzing genotype data. In the recent years, scientists have come up with high quantity genotyping technologies that are cost-effective and assist in understanding the genetic basis of phenotypes of interest. The presence of many SNPs has facilitated the success of statistical genetic studies. The first step in gene mapping used to be linkage analysis (Lin & Hongyu 103). SNPs that have close relationship as far as proximity is concerned can easily co-segregate as a result of linkage disequilibrium. Association mapping is based on theoretical allelic association, which has been more apparent in recent years. The two main approaches that scientists use to map genetic loci are association and linkage analyses. Factors that are

Sales Management Assignment Example | Topics and Well Written Essays - 2000 words

Sales Management - Assignment Example However this is not the case because they are being constantly let down by the sales managers and indeed the policy adopted by Mike Dalton. As Dalton believes in offering the sales representatives with the remuneration package alone and no salary, this stands as a very negative connotation of the entire payment structure. If for instance a sales representative is unable to find a single sales lead in a particular period of time, he would not receive any payments at all. It would mean that all his hard work and devotion for the sake of IFP would essentially go to waste. What is important is to understand how IFP can give its best to its own employees who are indeed receiving nothing at all, more so when they are being committed to the company and its stance in essence. There is a dire need to understand how IFP’s viewpoint would be taken over by the employees. I do not agree that the employees would be on their toes if they receive just the compensation for the sales leads that they bring in instead of the salaries that they should be getting (Weitzul 1993). This is a direct case of meting out differential treatment for the employees because they are being hard done by. Justice needs to be done so that they remain motivated and glued to their respective jobs. The remuneration package used by Mike Dalton might not serve the purpose of the sales representatives and indeed the employees at large because it does not warrant a just policy to meet their most basic needs at work. This should be done away with at the earliest so that the employees might heave a sigh of relief and work to their best effect in the future (Gunsch 1991). The sales team will always be at the mercy of their sales leads and they thus know that if they fall short on this count, they would be removed from their jobs and hence their termination would mean a lot of economic problems for not only their own selves